Symbol
Name
ID

Rb1
RB transcriptional corepressor 1
MGI:97874

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Mouse Phenotypes

abnormal milk ejection

abnormal neuroendocrine gland morphology

abnormal pituitary intermediate lobe morphology

pituitary intermediate lobe hyperplasia

mammary gland duct hyperplasia

mammary gland hyperplasia

decreased testis weight

small testis

increased pheochromocytoma incidence

increased pituitary gland tumor incidence

increased pituitary adenohypophysis tumor incidence

increased pituitary adenoma incidence

increased pituitary melanotroph tumor incidence

increased thyroid tumor incidence

increased thyroid C-cell carcinoma incidence

Availability

Mouse Genotype

Rb1^tm1Fad/Rb1^tm1Fad

Rb1^tm2.1Fad/Rb1^tm2.1Fad

Rb1^tm2.1Jyjw/Rb1^tm2.1Jyjw

Rb1^tm1Brd/Rb1⁺

Rb1^tm1Mlh/Rb1⁺

Rb1^tm1Tyj/Rb1⁺

Rb1^tm1Tyj/Rb1^tm2Tyj

Rb1^tm2Mlh/Rb1⁺

Rb1^tm1Brn/Rb1^tm1Brn
Tg(Pomc-FLP)1aBrn/0 (conditional)

Rb1^tm1Brn/Rb1^tm1Brn
X/Tg(Pomc-FLP)1bBrn (conditional)

Rb1^tm2Brn/Rb1^tm2Brn
Tg(Rbp3-cre)1Brn/0 (conditional)

Rb1^tm2Brn/Rb1^tm2Brn
Tg(Gfap-cre)2Brn/0 (conditional)

Rb1^tm3Tyj/Rb1^tm3Tyj
Tg(Nes-cre)1Atp/0 (conditional)

Ddx4^{tm1.1(cre)Dcp}/Ddx4⁺
Rb1^tm3Tyj/Rb1^tm3Tyj (conditional)

Rb1^tm1Brn/Rb1⁺
Tg(Pomc-FLP)1aBrn/0 (conditional)

Rb1^tm1Brn/Rb1⁺
X/Tg(Pomc-FLP)1bBrn (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23